CATH Classification

Domain Context

CATH Clusters

Superfamily Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain
Functional Family Histone-lysine N-methyltransferase SETD7

Enzyme Information

2.1.1.43
Histone-lysine N-methyltransferase.
based on mapping to UniProt Q8WTS6
S-adenosyl-L-methionine + L-lysine-[histone] = S-adenosyl-L-homocysteine + N(6)-methyl-L-lysine-[histone].

UniProtKB Entries (1)

Q8WTS6
SETD7_HUMAN
Homo sapiens
Histone-lysine N-methyltransferase SETD7

PDB Structure

PDB 3CBP
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Regulation of estrogen receptor alpha by the SET7 lysine methyltransferase.
Subramanian, K., Jia, D., Kapoor-Vazirani, P., Powell, D.R., Collins, R.E., Sharma, D., Peng, J., Cheng, X., Vertino, P.M.
Mol.Cell
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