CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.50 | Rossmann fold |
|
3.40.50.300 | P-loop containing nucleotide triphosphate hydrolases |
Domain Context
CATH Clusters
| Superfamily | P-loop containing nucleotide triphosphate hydrolases |
| Functional Family | Guanine nucleotide-binding protein G(q) subunit alpha |
Enzyme Information
UniProtKB Entries (3)
| P21279 |
GNAQ_MOUSE
Mus musculus
Guanine nucleotide-binding protein G(q) subunit alpha
|
| P10824 |
GNAI1_RAT
Rattus norvegicus
Guanine nucleotide-binding protein G(i) subunit alpha-1
|
| P63212 |
GBG2_BOVIN
Bos taurus
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2
|
PDB Structure
| PDB | 3AH8 |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Structural basis for the specific inhibition of heterotrimeric Gq protein by a small molecule.
Proc.Natl.Acad.Sci.USA
|
