×

Network disruptions

We have been experiencing disruptions on our local network which has affected the stability of these web pages. We have been working with IT support team to get this fixed as a matter of urgency and apologise for any inconvenience.

CATH Classification

Domain Context

CATH Clusters

Superfamily Nitrile hydratase alpha /Thiocyanate hydrolase gamma
Functional Family

Enzyme Information

4.2.1.84
Nitrile hydratase.
based on mapping to UniProt P13448
An aliphatic amide = a nitrile + H(2)O.
-!- Acts on short-chain aliphatic nitriles, converting them into the corresponding acid amides. -!- Does not act on these amides or on aromatic nitriles (cf. EC 3.5.5.1).

UniProtKB Entries (1)

P13449
NHAB_RHOER
Rhodococcus erythropolis
Nitrile hydratase subunit beta

PDB Structure

PDB 3A8M
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Kinetic and structural studies on roles of the serine ligand and a strictly conserved tyrosine residue in nitrile hydratase
Yamanaka, Y., Hashimoto, K., Ohtaki, A., Noguchi, K., Yohda, M., Odaka, M.
J.Biol.Inorg.Chem.
CATH-Gene3D is a Global Biodata Core Resource Learn more...