CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.30 | 2-Layer Sandwich |
|
3.30.565 | Heat Shock Protein 90 |
|
3.30.565.10 | Histidine kinase-like ATPase, C-terminal domain |
Domain Context
CATH Clusters
| Superfamily | Histidine kinase-like ATPase, C-terminal domain |
| Functional Family | Heat shock protein HSP 90-alpha |
Enzyme Information
UniProtKB Entries (1)
| P07900 |
HS90A_HUMAN
Homo sapiens
Heat shock protein HSP 90-alpha
|
PDB Structure
| PDB | 2YK2 |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Tricyclic Series of Heat Shock Protein 90 (Hsp90) Inhibitors Part I: Discovery of Tricyclic Imidazo[4,5-C]Pyridines as Potent Inhibitors of the Hsp90 Molecular Chaperone.
J.Med.Chem.
|