CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
1 | Mainly Alpha |
|
1.10 | Orthogonal Bundle |
|
1.10.437 | Apoptosis Regulator Bcl-x |
|
1.10.437.10 | Blc2-like |
Domain Context
CATH Clusters
| Superfamily | Blc2-like |
| Functional Family | Apoptosis regulator Bcl-2 |
Enzyme Information
UniProtKB Entries (2)
| P10415 |
BCL2_HUMAN
Homo sapiens
Apoptosis regulator Bcl-2
|
| Q07813 |
BAX_MOUSE
Mus musculus
Apoptosis regulator BAX
|
PDB Structure
| PDB | 2XA0 |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Evidence that Inhibition of Bax Activation by Bcl- 2 Involves its Tight and Preferential Interaction with the Bh3 Domain of Bax.
Cell Res.
|
