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1 keywords

CATH Domain 2winB03

CATH Classification

Level CATH Code Description
Class 2 Mainly Beta
Architecture 2.60 Sandwich
Topology 2.60.120 Jelly Rolls
Homologous Superfamily 2.60.120.1540  

Domain Context

CATH Clusters

Superfamily 2.60.120.1540
Functional Family Complement C3

Enzyme Information

UniProtKB Entries (2)

Q6GFB4
SCIN_STAAR
Staphylococcus aureus subsp. aureus MRSA252
Staphylococcal complement inhibitor
P00751
CFAB_HUMAN
Homo sapiens
Complement factor B

PDB Structure

PDB 2WIN
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structural and functional implications of the alternative complement pathway C3 convertase stabilized by a staphylococcal inhibitor.
Rooijakkers, S.H., Wu, J., Ruyken, M., van Domselaar, R., Planken, K.L., Tzekou, A., Ricklin, D., Lambris, J.D., Janssen, B.J., van Strijp, J.A., Gros, P.
Nat. Immunol.
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