CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.50 | Rossmann fold |
|
3.40.50.720 | NAD(P)-binding Rossmann-like Domain |
Domain Context
CATH Clusters
| Superfamily | NAD(P)-binding Rossmann-like Domain |
| Functional Family | Alanine dehydrogenase |
Enzyme Information
| 1.4.1.1 |
Alanine dehydrogenase.
based on mapping to UniProt P9WQB1
L-alanine + H(2)O + NAD(+) = pyruvate + NH(3) + NADH.
|
UniProtKB Entries (1)
| P9WQB1 |
DHA_MYCTU
Mycobacterium tuberculosis H37Rv
Alanine dehydrogenase
|
PDB Structure
| PDB | 2VHX |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Three-Dimensional Structures of Apo- and Holo-L-Alanine Dehydrogenase from Mycobacterium Tuberculosis Reveal Conformational Changes Upon Coenzyme Binding.
J.Mol.Biol.
|
