CATH Classification

Domain Context

CATH Clusters

Superfamily Cupin
Functional Family Lysine-specific demethylase 4A

Enzyme Information

1.14.11.-
With 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors.
based on mapping to UniProt O75164

UniProtKB Entries (1)

O75164
KDM4A_HUMAN
Homo sapiens
Lysine-specific demethylase 4A

PDB Structure

PDB 2VD7
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Inhibitor scaffolds for 2-oxoglutarate-dependent histone lysine demethylases.
Rose, N.R., Ng, S.S., Mecinovic, J., Lienard, B.M., Bello, S.H., Sun, Z., McDonough, M.A., Oppermann, U., Schofield, C.J.
J. Med. Chem.