CATH Domain 2v40A03

CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.90	Alpha-Beta Complex
	3.90.170	Adenylosuccinate Synthetase; Chain A, domain 3
	3.90.170.10	Adenylosuccinate Synthetase, subunit A, domain 3

Domain Context

CATH Clusters

Superfamily	Adenylosuccinate Synthetase, subunit A, domain 3
Functional Family	Adenylosuccinate synthetase

Enzyme Information

6.3.4.4

Adenylosuccinate synthase.

based on mapping to UniProt P30520

GTP + IMP + L-aspartate = GDP + phosphate + N(6)-(1,2-dicarboxyethyl)- AMP.

UniProtKB Entries (1)

PURA2_HUMAN

Homo sapiens

Adenylosuccinate synthetase isozyme 2

PDB Structure

PDB	2V40
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Human Adenylosuccinate Synthetase Isozyme 2 in Complex with Gdp Welin, M., Moche, M., Arrowsmith, C., Berglund, H., Busam, R., Collins, R., Dahlgren, L.G., Edwards, A., Flodin, S., Flores, A., Graslund, S., Hammarstrom, M., Hallberg, B.M., Holmberg-Schiavone, L., Johansson, I., Kallas, A., Karlberg, T., Kotenyova, T., Lehtio, L., Nyman, T., Ogg, D., Persson, C., Sagemark, J., Stenmark, P., Sundstrom, M., Thorsell, A.G., van den Berg, S., Weigelt, J., Nordlund, P. To be Published