CATH Domain 2qt0A00

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CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.40	3-Layer(aba) Sandwich
	3.40.50	Rossmann fold
	3.40.50.300	P-loop containing nucleotide triphosphate hydrolases

Domain Context

CATH Clusters

Superfamily	P-loop containing nucleotide triphosphate hydrolases
Functional Family	Nicotinamide riboside kinase 1

Enzyme Information

2.7.1.173	Nicotinate riboside kinase. based on mapping to UniProt Q9NWW6 ATP + beta-D-ribosylnicotinate = ADP + nicotinate beta-D-ribonucleotide. -!- The enzyme from yeast and human also has the activity of EC 2.7.1.22. -!- Formerly EC 2.7.1.n4.
2.7.1.22	Ribosylnicotinamide kinase. based on mapping to UniProt Q9NWW6 ATP + 1-(beta-D-ribofuranosyl)-nicotinamide = ADP + beta-nicotinamide D-ribonucleotide.

UniProtKB Entries (1)

NRK1_HUMAN

Homo sapiens

Nicotinamide riboside kinase 1

PDB Structure

PDB	2QT0
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism	Escherichia
Primary Citation	Nicotinamide Riboside Kinase Structures Reveal New Pathways to NAD(+). Tempel, W., Rabeh, W.M., Bogan, K.L., Belenky, P., Wojcik, M., Seidle, H.F., Nedyalkova, L., Yang, T., Sauve, A.A., Park, H.W., Brenner, C. Plos Biol.