CATH Domain 2q8sA00

CATH Classification

Level	CATH Code	Description
	1	Mainly Alpha
	1.10	Orthogonal Bundle
	1.10.565	Retinoid X Receptor
	1.10.565.10	Retinoid X Receptor

Domain Context

CATH Clusters

Superfamily	Retinoid X Receptor
Functional Family	Peroxisome proliferator-activated receptor gamma

Enzyme Information

UniProtKB Entries (1)

PPARG_HUMAN

Homo sapiens

Peroxisome proliferator-activated receptor gamma

PDB Structure

PDB	2Q8S
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Effects of modifications of the linker in a series of phenylpropanoic acid derivatives: Synthesis, evaluation as PPARalpha/gamma dual agonists, and X-ray crystallographic studies. Casimiro-Garcia, A., Bigge, C.F., Davis, J.A., Padalino, T., Pulaski, J., Ohren, J.F., McConnell, P., Kane, C.D., Royer, L.J., Stevens, K.A., Auerbach, B.J., Collard, W.T., McGregor, C., Fakhoury, S.A., Schaum, R.P., Zhou, H. Bioorg.Med.Chem.