CATH Classification

Domain Context

CATH Clusters

Superfamily 3.20.20.210
Functional Family Uroporphyrinogen decarboxylase

Enzyme Information

4.1.1.37
Uroporphyrinogen decarboxylase.
based on mapping to UniProt P06132
Uroporphyrinogen III = coproporphyrinogen + 4 CO(2).
-!- Acts on a number of porphyrinogens.

UniProtKB Entries (1)

P06132
DCUP_HUMAN
Homo sapiens
Uroporphyrinogen decarboxylase

PDB Structure

PDB 2Q6Z
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Two novel uroporphyrinogen decarboxylase (URO-D) mutations causing hepatoerythropoietic porphyria (HEP).
Phillips, J.D., Whitby, F.G., Stadtmueller, B.M., Edwards, C.Q., Hill, C.P., Kushner, J.P.
Transl.Res.
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