CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.30 | 2-Layer Sandwich |
|
3.30.930 | BirA Bifunctional Protein; domain 2 |
|
3.30.930.10 | Bira Bifunctional Protein; Domain 2 |
Domain Context
CATH Clusters
| Superfamily | Bira Bifunctional Protein; Domain 2 |
| Functional Family | Glycyl-tRNA synthetase 1 |
Enzyme Information
| 2.7.7.- |
Nucleotidyltransferases.
based on mapping to UniProt P41250
|
| 6.1.1.14 |
Glycine--tRNA ligase.
based on mapping to UniProt P41250
ATP + glycine + tRNA(Gly) = AMP + diphosphate + glycyl-tRNA(Gly).
|
UniProtKB Entries (1)
| P41250 |
GARS_HUMAN
Homo sapiens
Glycine--tRNA ligase
|
PDB Structure
| PDB | 2Q5I |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | Escherichia |
| Primary Citation |
Crystal structure of human wildtype and S581L-mutant glycyl-tRNA synthetase, an enzyme underlying distal spinal muscular atrophy.
Febs Lett.
|
