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1 keywords

CATH Domain 2pzaA00

CATH Classification

Level CATH Code Description
Class 3 Alpha Beta
Architecture 3.40 3-Layer(aba) Sandwich
Topology 3.40.50 Rossmann fold
Homologous Superfamily 3.40.50.620 HUPs

Domain Context

CATH Clusters

Superfamily HUPs
Functional Family NH(3)-dependent NAD(+) synthetase

Enzyme Information

6.3.1.5
NAD(+) synthase.
based on mapping to UniProt Q81RP3
ATP + deamido-NAD(+) + NH(3) = AMP + diphosphate + NAD(+).
-!- L-glutamine also acts, more slowly, as amido-donor (cf. EC 6.3.5.1).

UniProtKB Entries (1)

Q81RP3
NADE_BACAN
Bacillus anthracis
NH(3)-dependent NAD(+) synthetase

PDB Structure

PDB 2PZA
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Structural adaptation of an interacting non-native C-terminal helical extension revealed in the crystal structure of NAD(+) synthetase from Bacillus anthracis.
McDonald, H.M., Pruett, P.S., Deivanayagam, C., Protasevich, I.I., Carson, W.M., DeLucas, L.J., Brouillette, W.J., Brouillette, C.G.
Acta Crystallogr.,Sect.D
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