CATH Domain 2pi0C01

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CATH Classification

Level	CATH Code	Description
	1	Mainly Alpha
	1.10	Orthogonal Bundle
	1.10.10	Arc Repressor Mutant, subunit A
	1.10.10.10	Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain

Domain Context

CATH Clusters

Superfamily	Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain
Functional Family	Interferon regulatory factor 3

Enzyme Information

UniProtKB Entries (1)

IRF3_HUMAN

Homo sapiens

Interferon regulatory factor 3

PDB Structure

PDB	2PI0
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism	Escherichia
Primary Citation	Structure of IRF-3 bound to the PRDIII-I regulatory element of the human interferon-beta enhancer. Escalante, C.R., Nistal-Villan, E., Shen, L., Garcia-Sastre, A., Aggarwal, A.K. Mol.Cell