CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
1 | Mainly Alpha |
|
1.20 | Up-down Bundle |
|
1.20.900 | Dbl Homology Domain; Chain A |
|
1.20.900.10 | Dbl homology (DH) domain |
Domain Context
CATH Clusters
| Superfamily | Dbl homology (DH) domain |
| Functional Family | Guanine nucleotide exchange factor DBS |
Enzyme Information
| 2.7.11.1 |
Non-specific serine/threonine protein kinase.
based on mapping to UniProt O75962
ATP + a protein = ADP + a phosphoprotein.
-!- This is a heterogeneous group of serine/threonine protein kinases that do not have an activating compound and are either non-specific or their specificity has not been analyzed to date. -!- Formerly EC 2.7.1.37 and EC 2.7.1.70.
|
UniProtKB Entries (1)
| O75962 |
TRIO_HUMAN
Homo sapiens
Triple functional domain protein
|
PDB Structure
| PDB | 2NZ8 |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | Escherichia |
| Primary Citation |
The DH and PH Domains of Trio Coordinately Engage Rho GTPases for their Efficient Activation
J.Mol.Biol.
|
