CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
1 | Mainly Alpha |
|
1.10 | Orthogonal Bundle |
|
1.10.238 | Recoverin; domain 1 |
|
1.10.238.10 | EF-hand |
Domain Context
CATH Clusters
| Superfamily | EF-hand |
| Functional Family | Troponin C, slow skeletal and cardiac muscles |
Enzyme Information
UniProtKB Entries (1)
| P63316 |
TNNC1_HUMAN
Homo sapiens
Troponin C, slow skeletal and cardiac muscles
|
PDB Structure
| PDB | 2MLE |
| External Links | |
| Method | SOLUTION NMR |
| Organism | |
| Primary Citation |
The dilated cardiomyopathy G159D mutation in cardiac troponin C weakens the anchoring interaction with troponin I.
Biochemistry
|
