CATH Domain 2l6uA00

×

Network disruptions

We have been experiencing disruptions on our local network which has affected the stability of these web pages. We have been working with IT support team to get this fixed as a matter of urgency and apologise for any inconvenience.

CATH Classification

Level	CATH Code	Description
	2	Mainly Beta
	2.40	Beta Barrel
	2.40.290	Ku70; Chain: A; Domain 2
	2.40.290.30	Mediator complex subunit 25, ACID domain

Domain Context

CATH Clusters

Superfamily	Mediator complex subunit 25, ACID domain
Functional Family	Mediator of RNA polymerase II transcription subunit 25

Enzyme Information

UniProtKB Entries (1)

MED25_HUMAN

Homo sapiens

Mediator of RNA polymerase II transcription subunit 25

PDB Structure

PDB	2L6U
External Links	PDBSum Proteopedia
Method	SOLUTION NMR
Organism
Primary Citation	Solution NMR structure of MED25(391-543) comprising the activator-interacting domain (ACID) of human mediator subunit 25. Eletsky, A., Ruyechan, W.T., Xiao, R., Acton, T.B., Montelione, G.T., Szyperski, T. J.Struct.Funct.Genom.