CATH Domain 2l2lA00

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CATH Classification

Level	CATH Code	Description
	6	Special
	6.10	Helix non-globular
	6.10.250	Single alpha-helices involved in coiled-coils or other helix-helix interfaces
	6.10.250.1650

Domain Context

CATH Clusters

Superfamily	6.10.250.1650
Functional Family

Enzyme Information

UniProtKB Entries (1)

MBD2_HUMAN

Homo sapiens

Methyl-CpG-binding domain protein 2

PDB Structure

PDB	2L2L
External Links	PDBSum Proteopedia
Method	SOLUTION NMR
Organism
Primary Citation	p66Alpha-MBD2 coiled-coil interaction and recruitment of Mi-2 are critical for globin gene silencing by the MBD2-NuRD complex. Gnanapragasam, M.N., Scarsdale, J.N., Amaya, M.L., Webb, H.D., Desai, M.A., Walavalkar, N.M., Wang, S.Z., Zu Zhu, S., Ginder, G.D., Williams, D.C. Proc.Natl.Acad.Sci.USA