CATH Domain 2kzaA00

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CATH Classification

Level	CATH Code	Description
	4	Few Secondary Structures
	4.10	Irregular
	4.10.760	Agouti Related Protein; Chain A
	4.10.760.10	Agouti domain

Domain Context

CATH Clusters

Superfamily	Agouti domain
Functional Family	Agouti-signaling protein

Enzyme Information

UniProtKB Entries (1)

ASIP_HUMAN

Homo sapiens

Agouti-signaling protein

PDB Structure

PDB	2KZA
External Links	PDBSum Proteopedia
Method	SOLUTION NMR
Organism
Primary Citation	Loop-swapped chimeras of the agouti-related protein and the agouti signaling protein identify contacts required for melanocortin 1 receptor selectivity and antagonism. Patel, M.P., Cribb Fabersunne, C.S., Yang, Y.K., Kaelin, C.B., Barsh, G.S., Millhauser, G.L. J.Mol.Biol.