CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
2 | Mainly Beta |
|
2.30 | Roll |
|
2.30.42 | Pdz3 Domain |
|
2.30.42.10 | PDZ domain |
Domain Context
CATH Clusters
| Superfamily | 2.30.42.10 |
| Functional Family | Na(+)/H(+) exchange regulatory cofactor NHE-RF |
Enzyme Information
UniProtKB Entries (1)
| O14745 |
NHRF1_HUMAN
Homo sapiens
Na(+)/H(+) exchange regulatory cofactor NHE-RF1
|
PDB Structure
| PDB | 2KRG |
| External Links | |
| Method | SOLUTION NMR |
| Organism | |
| Primary Citation |
A conformational switch in the sodium/ hydrogen exchange regulatory factor 1(NHERF1) controls autoinhibition and complex formation.
J.Biol.Chem.
|
