CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.1110 | Calcium-transporting ATPase, cytoplasmic domain N |
|
3.40.1110.10 | Calcium-transporting ATPase, cytoplasmic domain N |
Domain Context
CATH Clusters
| Superfamily | Calcium-transporting ATPase, cytoplasmic domain N |
| Functional Family | Copper-transporting ATPase 1, putative |
Enzyme Information
| 7.2.2.8 |
P-type Cu(+) transporter.
based on mapping to UniProt Q04656
ATP + H(2)O + Cu(+)(Side 1) = ADP + phosphate + Cu(+)(Side 2).
-!- A P-type ATPase that undergoes covalent phosphorylation during the transport cycle. -!- This enzyme transports Cu(+) or Ag(+), and cannot transport the divalent ions, contrary to EC 7.2.2.9, which mainly transports the divalent copper ion. -!- Formerly EC 3.6.3.54.
|
UniProtKB Entries (1)
| Q04656 |
ATP7A_HUMAN
Homo sapiens
Copper-transporting ATPase 1
|
PDB Structure
| PDB | 2KMX |
| External Links | |
| Method | SOLUTION NMR |
| Organism | |
| Primary Citation |
The binding mode of ATP revealed by the solution structure of the N-domain of human ATP7A.
J.Biol.Chem.
|