CATH Domain 2kbyA00

CATH Classification

Level	CATH Code	Description
	4	Few Secondary Structures
	4.10	Irregular
	4.10.170	p53, subunit A
	4.10.170.10	p53-like tetramerisation domain

Domain Context

CATH Clusters

Superfamily	p53-like tetramerisation domain
Functional Family	Cellular tumor antigen p53

Enzyme Information

UniProtKB Entries (1)

P73_HUMAN

Homo sapiens

Tumor protein p73

PDB Structure

PDB	2KBY
External Links	PDBSum Proteopedia
Method	SOLUTION NMR
Organism
Primary Citation	Conformational stability and activity of p73 require a second helix in the tetramerization domain. Coutandin, D., Lohr, F., Niesen, F.H., Ikeya, T., Weber, T.A., Schafer, B., Zielonka, E.M., Bullock, A.N., Yang, A., Guntert, P., Knapp, S., McKeon, F., Ou, H.D., Dotsch, V. Cell Death Differ.