CATH Classification

Domain Context

CATH Clusters

Superfamily 3.40.1190.20
Functional Family Adenosine kinase

Enzyme Information

2.7.1.20
Adenosine kinase.
based on mapping to UniProt P55263
ATP + adenosine = ADP + AMP.
-!- 2-aminoadenosine can also act as acceptor.

UniProtKB Entries (1)

P55263
ADK_HUMAN
Homo sapiens
Adenosine kinase

PDB Structure

PDB 2I6B
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Crystal structures of human adenosine kinase inhibitor complexes reveal two distinct binding modes.
Muchmore, S.W., Smith, R.A., Stewart, A.O., Cowart, M.D., Gomtsyan, A., Matulenko, M.A., Yu, H., Severin, J.M., Bhagwat, S.S., Lee, C.H., Kowaluk, E.A., Jarvis, M.F., Jakob, C.L.
J.Med.Chem.