CATH Classification

Domain Context

CATH Clusters

Superfamily Glutaredoxin
Functional Family Glutathione peroxidase

Enzyme Information

1.11.1.9
Glutathione peroxidase.
based on mapping to UniProt O75715
2 glutathione + H(2)O(2) = glutathione disulfide + 2 H(2)O.
-!- Steroid and lipid hydroperoxides, but not the product of reaction of EC 1.13.11.12 on phospholipids, can act as acceptor, but more slowly than H(2)O(2) (cf. EC 1.11.1.12).

UniProtKB Entries (1)

O75715
GPX5_HUMAN
Homo sapiens
Epididymal secretory glutathione peroxidase

PDB Structure

PDB 2I3Y
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Crystal structure of human glutathione peroxidase 5
Kavanagh, K.L., Oppermann, U.
To be published
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