CATH Domain 2h62B00

CATH Classification

Level	CATH Code	Description
	2	Mainly Beta
	2.10	Ribbon
	2.10.90	Cystine Knot Cytokines, subunit B
	2.10.90.10	Cystine-knot cytokines

Domain Context

CATH Clusters

Superfamily	Cystine-knot cytokines
Functional Family

Enzyme Information

UniProtKB Entries (1)

BMP2_HUMAN

Homo sapiens

Bone morphogenetic protein 2

PDB Structure

PDB	2H62
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism	Escherichia
Primary Citation	A silent H-bond can be mutationally activated for high-affinity interaction of BMP-2 and activin type IIB receptor. Weber, D., Kotzsch, A., Nickel, J., Harth, S., Seher, A., Mueller, U., Sebald, W., Mueller, T.D. Bmc Struct.Biol.