CATH Domain 2gtpB01

CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.40	3-Layer(aba) Sandwich
	3.40.50	Rossmann fold
	3.40.50.300	P-loop containing nucleotide triphosphate hydrolases

Domain Context

CATH Clusters

Superfamily	P-loop containing nucleotide triphosphate hydrolases
Functional Family	Guanine nucleotide-binding protein G(i) subunit alpha-1

Enzyme Information

UniProtKB Entries (1)

RGS1_HUMAN

Homo sapiens

Regulator of G-protein signaling 1

PDB Structure

PDB	2GTP
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism	Escherichia
Primary Citation	Structural diversity in the RGS domain and its interaction with heterotrimeric G protein alpha-subunits. Soundararajan, M., Willard, F.S., Kimple, A.J., Turnbull, A.P., Ball, L.J., Schoch, G.A., Gileadi, C., Fedorov, O.Y., Dowler, E.F., Higman, V.A., Hutsell, S.Q., Sundstrom, M., Doyle, D.A., Siderovski, D.P. Proc.Natl.Acad.Sci.Usa