CATH Classification

Domain Context

CATH Clusters

Superfamily Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 1
Functional Family Trans-2,3-enoyl-CoA reductase b

Enzyme Information

1.3.1.93
Very-long-chain enoyl-CoA reductase.
based on mapping to UniProt Q9NZ01
A very-long-chain acyl-CoA + NADP(+) = a very-long-chain trans-2,3- dehydroacyl-CoA + NADPH.
-!- This is the fourth component of the elongase, a microsomal protein complex responsible for extending palmitoyl-CoA and stearoyl-CoA (and modified forms thereof) to very-long-chain acyl CoAs. -!- Cf. EC 2.3.1.199, EC 1.1.1.330 and EC 4.2.1.134. -!- Formerly EC 2.3.1.119.

UniProtKB Entries (1)

Q9NZ01
TECR_HUMAN
Homo sapiens
Very-long-chain enoyl-CoA reductase

PDB Structure

PDB 2DZJ
External Links
Method SOLUTION NMR
Organism
Primary Citation
2DZJ/Solution Structure of the N-terminal Ubiquitin-like Domain in Human Synaptic Glycoprotein SC2
Zhao, C., Yoneyama, M., Koshiba, S., Watanabe, S., Harada, T., Kigawa, T., Yokoyama, S.
To be Published