CATH Classification
Level | CATH Code | Description |
---|---|---|
2 | Mainly Beta | |
2.60 | Sandwich | |
2.60.40 | Immunoglobulin-like | |
2.60.40.10 | Immunoglobulins |
Domain Context
CATH Clusters
Superfamily | Immunoglobulins |
Functional Family | MER proto-oncogene, tyrosine kinase |
Enzyme Information
2.7.10.1 |
Receptor protein-tyrosine kinase.
based on mapping to UniProt Q12866
ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate.
-!- The receptor protein-tyrosine kinases, which can be defined as having a transmembrane domain, are a large and diverse multigene family found only in metazoans. -!- In the human genome, 58 receptor-type protein-tyrosine kinases have been identified and these are distributed into 20 subfamilies. -!- Formerly EC 2.7.1.112.
|
UniProtKB Entries (1)
Q12866 |
MERTK_HUMAN
Homo sapiens
Tyrosine-protein kinase Mer
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PDB Structure
PDB | 2DBJ |
External Links | |
Method | SOLUTION NMR |
Organism | |
Primary Citation |
Solution structures of the fn3 domain of human Proto-oncogene tyrosine-protein kinase MER precursor
To be Published
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