CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.20 | Alpha-Beta Barrel |
|
3.20.10 | D-amino Acid Aminotransferase; Chain A, domain 2 |
|
3.20.10.10 | D-amino Acid Aminotransferase, subunit A, domain 2 |
Domain Context
CATH Clusters
| Superfamily | D-amino Acid Aminotransferase, subunit A, domain 2 |
| Functional Family | Branched-chain-amino-acid aminotransferase |
Enzyme Information
| 2.6.1.42 |
Branched-chain-amino-acid transaminase.
based on mapping to UniProt P54687
L-leucine + 2-oxoglutarate = 4-methyl-2-oxopentanoate + L-glutamate.
-!- Also acts on L-isoleucine and L-valine. -!- Different from EC 2.6.1.66.
|
UniProtKB Entries (1)
| P54687 |
BCAT1_HUMAN
Homo sapiens
Branched-chain-amino-acid aminotransferase, cytosolic
|
PDB Structure
| PDB | 2COI |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | Escherichia |
| Primary Citation |
Structural determinants for branched-chain aminotransferase isozyme-specific inhibition by the anticonvulsant drug gabapentin
J.Biol.Chem.
|