CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.50 | Rossmann fold |
|
3.40.50.170 | Formyl transferase, N-terminal domain |
Domain Context
CATH Clusters
| Superfamily | Formyl transferase, N-terminal domain |
| Functional Family | 10-formyltetrahydrofolate dehydrogenase |
Enzyme Information
| 1.5.1.6 |
Formyltetrahydrofolate dehydrogenase.
based on mapping to UniProt O75891
10-formyltetrahydrofolate + NADP(+) + H(2)O = tetrahydrofolate + CO(2) + NADPH.
|
UniProtKB Entries (1)
| O75891 |
AL1L1_HUMAN
Homo sapiens
Cytosolic 10-formyltetrahydrofolate dehydrogenase
|
PDB Structure
| PDB | 2CFI |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Structures of the Hydrolase Domain of Human 10-Formyltetrahydrofolate Dehydrogenase and its Complex with a Substrate Analogue.
Acta Crystallogr.,Sect.D
|
