CATH Domain 2ccgB00

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CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.40	3-Layer(aba) Sandwich
	3.40.50	Rossmann fold
	3.40.50.300	P-loop containing nucleotide triphosphate hydrolases

Domain Context

CATH Clusters

Superfamily	P-loop containing nucleotide triphosphate hydrolases
Functional Family	Thymidylate kinase

Enzyme Information

2.7.4.9

dTMP kinase.

based on mapping to UniProt P65248

ATP + dTMP = ADP + dTDP.

UniProtKB Entries (1)

KTHY_STAAM

Staphylococcus aureus subsp. aureus Mu50

Thymidylate kinase

PDB Structure

PDB	2CCG
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Structures of S. Aureus Thymidylate Kinase Reveal an Atypical Active Site Configuration and an Intermediate Conformational State Upon Substrate Binding Kotaka, M., Dhaliwal, B., Ren, J., Nichols, C.E., Angell, R., Lockyer, M., Hawkins, A.R., Stammers, D.K. Protein Sci.