CATH Domain 2b2xA00

CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.40	3-Layer(aba) Sandwich
	3.40.50	Rossmann fold
	3.40.50.410	von Willebrand factor, type A domain

Domain Context

CATH Clusters

Superfamily	von Willebrand factor, type A domain
Functional Family	Integrin, alpha 10

Enzyme Information

UniProtKB Entries (1)

ITA1_RAT

Rattus norvegicus

Integrin alpha-1

PDB Structure

PDB	2B2X
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism	Escherichia
Primary Citation	Affinity enhancement of an in vivo matured therapeutic antibody using structure-based computational design Clark, L.A., Boriack-Sjodin, P.A., Eldredge, J., Fitch, C., Friedman, B., Hanf, K.J., Jarpe, M., Liparoto, S.F., Li, Y., Lugovskoy, A., Miller, S., Rushe, M., Sherman, W., Simon, K., Van Vlijmen, H. Protein Sci.