CATH Classification

Domain Context

CATH Clusters

Superfamily q2cbj1_9rhob like domain
Functional Family Phytanoyl-CoA dioxygenase, peroxisomal

Enzyme Information

1.14.11.18
Phytanoyl-CoA dioxygenase.
based on mapping to UniProt O14832
Phytanoyl-CoA + 2-oxoglutarate + O(2) = 2-hydroxyphytanoyl-CoA + succinate + CO(2).
-!- Part of the peroxisomal phytanic acid alpha-oxidation pathway.

UniProtKB Entries (1)

O14832
PAHX_HUMAN
Homo sapiens
Phytanoyl-CoA dioxygenase, peroxisomal

PDB Structure

PDB 2A1X
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Structure of Human Phytanoyl-CoA 2-Hydroxylase Identifies Molecular Mechanisms of Refsum Disease
McDonough, M.A., Kavanagh, K.L., Butler, D., Searles, T., Oppermann, U., Schofield, C.J.
J.Biol.Chem.