CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.47 | Peroxisomal Thiolase; Chain A, domain 1 |
|
3.40.47.10 | Thiolase/Chalcone synthase |
Domain Context
CATH Clusters
| Superfamily | 3.40.47.10 |
| Functional Family |
Enzyme Information
| 2.3.3.10 |
Hydroxymethylglutaryl-CoA synthase.
based on mapping to UniProt Q9FD71
Acetyl-CoA + H(2)O + acetoacetyl-CoA = (S)-3-hydroxy-3-methylglutaryl-CoA + CoA.
-!- Formerly EC 4.1.3.5.
|
UniProtKB Entries (1)
| Q9FD71 |
HMGCS_ENTFL
Enterococcus faecalis
Hydroxymethylglutaryl-CoA synthase
|
PDB Structure
| PDB | 1YSL |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | Escherichia |
| Primary Citation |
X-ray Crystal Structures of HMG-CoA Synthase from Enterococcus faecalis and a Complex with Its Second Substrate/Inhibitor Acetoacetyl-CoA.
Biochemistry
|
