CATH Domain 1y5oA00

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CATH Classification

Level	CATH Code	Description
	2	Mainly Beta
	2.30	Roll
	2.30.29	PH-domain like
	2.30.29.30	Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)

Domain Context

CATH Clusters

Superfamily	Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)
Functional Family	Transcription initiation factor TFIIH subunit

Enzyme Information

UniProtKB Entries (1)

TFB1_YEAST

Saccharomyces cerevisiae S288C

General transcription and DNA repair factor IIH subunit TFB1

PDB Structure

PDB	1Y5O
External Links	PDBSum Proteopedia
Method	SOLUTION NMR
Organism	Escherichia
Primary Citation	NMR Structure of the Amino-Terminal Domain from the Tfb1 Subunit of TFIIH and Characterization of Its Phosphoinositide and VP16 Binding Sites Di Lello, P., Nguyen, B.D., Jones, T.N., Potempa, K., Kobor, M.S., Legault, P., Omichinski, J.G. Biochemistry