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1 keywords

CATH Domain 1xv8A01

CATH Classification

Level CATH Code Description
Class 3 Alpha Beta
Architecture 3.20 Alpha-Beta Barrel
Topology 3.20.20 TIM Barrel
Homologous Superfamily 3.20.20.80 Glycosidases

Domain Context

CATH Clusters

Superfamily Glycosidases
Functional Family Pancreatic alpha-amylase

Enzyme Information

3.2.1.1
Alpha-amylase.
based on mapping to UniProt P04745
Endohydrolysis of (1->4)-alpha-D-glucosidic linkages in polysaccharides containing three or more (1->4)-alpha-linked D-glucose units.
-!- Acts on starch, glycogen and related polysaccharides and oligosaccharides in a random manner; reducing groups are liberated in the alpha-configuration. -!- The term 'alpha' relates to the initial anomeric configuration of the free sugar group released and not to the configuration of the linkage hydrolyzed.

UniProtKB Entries (1)

P04745
AMY1_HUMAN
Homo sapiens
Alpha-amylase 1

PDB Structure

PDB 1XV8
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Crystal Structure of Human Salivary Alpha-Amylase Dimer
Fisher, S.Z., Govindasamy, L., Tu, C.K., Silverman, D.N., Rajaniemi, H., McKenna, R.
To be Published
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