CATH Domain 1wseA00

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CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.30	2-Layer Sandwich
	3.30.420	Nucleotidyltransferase; domain 5
	3.30.420.10	Ribonuclease H-like superfamily/Ribonuclease H

Domain Context

CATH Clusters

Superfamily	Ribonuclease H-like superfamily/Ribonuclease H
Functional Family	Ribonuclease H

Enzyme Information

3.1.26.4

Ribonuclease H.

based on mapping to UniProt P0A7Y4

Endonucleolytic cleavage to 5'-phosphomonoester.

-!- Acts on RNA-DNA hybrids.

UniProtKB Entries (1)

RNH_ECOLI

Escherichia coli K-12

Ribonuclease HI

PDB Structure

PDB	1WSE
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism	Escherichia
Primary Citation	Identification of Single Mn(2+) Binding Sites Required for Activation of the Mutant Proteins of E.coli RNase HI at Glu48 and/or Asp134 by X-ray Crystallography Tsunaka, Y., Takano, K., Matsumura, H., Yamagata, Y., Kanaya, S. J.Mol.Biol.