CATH Domain 1wkwA00

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CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.30	2-Layer Sandwich
	3.30.760	RNA Cap, Translation Initiation Factor Eif4e
	3.30.760.10	RNA Cap, Translation Initiation Factor Eif4e

Domain Context

CATH Clusters

Superfamily	RNA Cap, Translation Initiation Factor Eif4e
Functional Family	Eukaryotic translation initiation factor 4E

Enzyme Information

UniProtKB Entries (1)

IF4E_HUMAN

Homo sapiens

Eukaryotic translation initiation factor 4E

PDB Structure

PDB	1WKW
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism	Escherichia
Primary Citation	Structural basis for mRNA Cap-Binding regulation of eukaryotic initiation factor 4E by 4E-binding protein, studied by spectroscopic, X-ray crystal structural, and molecular dynamics simulation methods Tomoo, K., Matsushita, Y., Fujisaki, H., Abiko, F., Shen, X., Taniguchi, T., Miyagawa, H., Kitamura, K., Miura, K., Ishida, T. Biochim.Biophys.Acta