CATH Domain 1v3qE00

CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.40	3-Layer(aba) Sandwich
	3.40.50	Rossmann fold
	3.40.50.1580	Nucleoside phosphorylase domain

Domain Context

CATH Clusters

Superfamily	Nucleoside phosphorylase domain
Functional Family

Enzyme Information

2.4.2.1

Purine-nucleoside phosphorylase.

based on mapping to UniProt P00491

(1) Purine nucleoside + phosphate = purine + alpha-D-ribose 1-phosphate. (2) Purine deoxynucleoside + phosphate = purine + 2'-deoxy-alpha-D-ribose 1-phosphate.

-!- Specificity not completely determined. -!- Can also catalyze ribosyltransferase reactions of the type catalyzed by EC 2.4.2.5.

UniProtKB Entries (1)

P00491

PNPH_HUMAN

Homo sapiens

Purine nucleoside phosphorylase

PDB Structure

PDB	1V3Q
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism	Escherichia
Primary Citation	Structures of human purine nucleoside phosphorylase complexed with inosine and ddI Canduri, F., dos Santos, D.M., Silva, R.G., Mendes, M.A., Basso, L.A., Palma, M.S., de Azevedo Jr., W.F., Santos, D.S. Biochem.Biophys.Res.Commun.