CATH Domain 1uxhB02

Level	CATH Code	Description
	3	Alpha Beta
	3.90	Alpha-Beta Complex
	3.90.110	L-2-Hydroxyisocaproate Dehydrogenase; Chain A, domain 2
	3.90.110.10	Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal

Superfamily	Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal
Functional Family	Malate dehydrogenase

1.1.1.37

Malate dehydrogenase.

based on mapping to UniProt P80040

(S)-malate + NAD(+) = oxaloacetate + NADH.

-!- Also oxidizes some other 2-hydroxydicarboxylic acids.

MDH_CHLAA

Chloroflexus aurantiacus J-10-fl

Malate dehydrogenase

PDB	1UXH
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Large Improvement in the Thermal Stability of a Tetrameric Malate Dehydrogenase by Single Point Mutations at the Dimer-Dimer Interface. Bjork, A., Dalhus, B., Mantzilas, D., Sirevag, R., Eijsink, V.G.H. J.Mol.Biol.