CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
2 | Mainly Beta |
|
2.40 | Beta Barrel |
|
2.40.70 | Cathepsin D, subunit A; domain 1 |
|
2.40.70.10 | Acid Proteases |
Domain Context
CATH Clusters
| Superfamily | Acid Proteases |
| Functional Family | Cathepsin E |
Enzyme Information
| 3.4.23.34 |
Cathepsin E.
based on mapping to UniProt P14091
Similar to cathepsin D, but slightly broader specificity.
-!- Found in stomach, spleen, erythrocyte membrane; not lysosomal. -!- Pro-cathepsin E is an 86 kDa disulfide-linked dimer; activation or reduction produces monomers. -!- Belongs to peptidase family A1.
|
UniProtKB Entries (1)
| P14091 |
CATE_HUMAN
Homo sapiens
Cathepsin E
|
PDB Structure
| PDB | 1TZS |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | Escherichia |
| Primary Citation |
Crystal structure of an activation intermediate of cathepsin e
J.Mol.Biol.
|