CATH Classification

Domain Context

CATH Clusters

Superfamily TAFII-230 TBP-binding domain
Functional Family Transcription initiation factor TFIID subunit

Enzyme Information

2.7.11.1
Non-specific serine/threonine protein kinase.
based on mapping to UniProt P51123
ATP + a protein = ADP + a phosphoprotein.
-!- This is a heterogeneous group of serine/threonine protein kinases that do not have an activating compound and are either non-specific or their specificity has not been analyzed to date. -!- Formerly EC 2.7.1.37 and EC 2.7.1.70.

UniProtKB Entries (2)

P13393
TBP_YEAST
Saccharomyces cerevisiae S288C
TATA-box-binding protein
P51123
TAF1_DROME
Drosophila melanogaster
Transcription initiation factor TFIID subunit 1

PDB Structure

PDB 1TBA
External Links
Method SOLUTION NMR
Organism Escherichia
Primary Citation
Solution structure of a TBP-TAF(II)230 complex: protein mimicry of the minor groove surface of the TATA box unwound by TBP.
Liu, D., Ishima, R., Tong, K.I., Bagby, S., Kokubo, T., Muhandiram, D.R., Kay, L.E., Nakatani, Y., Ikura, M.
Cell(Cambridge,Mass.)
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