CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
1 | Mainly Alpha |
|
1.20 | Up-down Bundle |
|
1.20.5 | Single alpha-helices involved in coiled-coils or other helix-helix interfaces |
|
1.20.5.170 |
Domain Context
CATH Clusters
| Superfamily | 1.20.5.170 |
| Functional Family | Cyclic AMP-dependent transcription factor ATF-2 |
Enzyme Information
| 2.3.1.48 |
Histone acetyltransferase.
based on mapping to UniProt P15336
Acetyl-CoA + [protein]-L-lysine = CoA + [protein]-N(6)-acetyl-L-lysine.
-!- A group of enzymes acetylating histones. -!- Several of the enzymes can also acetylate lysines in other proteins.
|
UniProtKB Entries (1)
| Q14653 |
IRF3_HUMAN
Homo sapiens
Interferon regulatory factor 3
|
PDB Structure
| PDB | 1T2K |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | Escherichia |
| Primary Citation |
Crystal structure of ATF-2/c-Jun and IRF-3 bound to the interferon-beta enhancer.
Embo J.
|
