CATH Classification
Level | CATH Code | Description |
---|---|---|
3 | Alpha Beta | |
3.40 | 3-Layer(aba) Sandwich | |
3.40.50 | Rossmann fold | |
3.40.50.1580 | Nucleoside phosphorylase domain |
Domain Context
CATH Clusters
Superfamily | Nucleoside phosphorylase domain |
Functional Family | Purine nucleoside phosphorylase |
Enzyme Information
2.4.2.28 |
S-methyl-5'-thioadenosine phosphorylase.
based on mapping to UniProt Q13126
S-methyl-5'-thioadenosine + phosphate = adenine + S-methyl-5-thio-alpha- D-ribose 1-phosphate.
-!- Also acts on 5'-deoxyadenosine and other analogs having 5'-deoxy groups.
|
UniProtKB Entries (1)
Q13126 |
MTAP_HUMAN
Homo sapiens
S-methyl-5'-thioadenosine phosphorylase
|
PDB Structure
PDB | 1SD1 |
External Links | |
Method | X-RAY DIFFRACTION |
Organism | Escherichia |
Primary Citation |
Structural Comparison of MTA Phosphorylase and MTA/AdoHcy Nucleosidase Explains Substrate Preferences and Identifies Regions Exploitable for Inhibitor Design.
Biochemistry
|