CATH Classification

Domain Context

CATH Clusters

Superfamily Paired amphipathic helix
Functional Family Paired amphipathic helix protein Sin3a

Enzyme Information

UniProtKB Entries (2)

Q60520
SIN3A_MOUSE
Mus musculus
Paired amphipathic helix protein Sin3a
Q05195
MAD1_HUMAN
Homo sapiens
Max dimerization protein 1

PDB Structure

PDB 1S5Q
External Links
Method SOLUTION NMR
Organism Escherichia
Primary Citation
HBP1 and Mad1 repressors bind the Sin3 corepressor PAH2 domain with opposite helical orientations.
Swanson, K.A., Knoepfler, P.S., Huang, K., Kang, R.S., Cowley, S.M., Laherty, C.D., Eisenman, R.N., Radhakrishnan, I.
Nat.Struct.Mol.Biol.