CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.10 | Roll |
|
3.10.450 | Nuclear Transport Factor 2; Chain: A, |
|
3.10.450.30 | Microbial ribonucleases |
Domain Context
CATH Clusters
| Superfamily | Microbial ribonucleases |
| Functional Family | Guanyl-specific ribonuclease T1 |
Enzyme Information
| 3.1.27.3 |
Ribonuclease T(1).
based on mapping to UniProt P00651
Two-stage endonucleolytic cleavage to nucleoside 3'-phosphates and 3'-phosphooligonucleotides ending in G-P with 2',3'-cyclic phosphate intermediates.
-!- Formerly EC 2.7.7.26 and EC 3.1.4.8.
|
UniProtKB Entries (1)
| P00651 |
RNT1_ASPOR
Aspergillus oryzae RIB40
Guanyl-specific ribonuclease T1
|
PDB Structure
| PDB | 1RLS |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Crystal structure of RNase T1 complexed with the product nucleotide 3'-GMP. Structural evidence for direct interaction of histidine 40 and glutamic acid 58 with the 2'-hydroxyl group of the ribose.
J.Biol.Chem.
|
