CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.50 | Rossmann fold |
|
3.40.50.720 | NAD(P)-binding Rossmann-like Domain |
Domain Context
CATH Clusters
| Superfamily | NAD(P)-binding Rossmann-like Domain |
| Functional Family | NEDD8-activating enzyme E1 catalytic subunit, putative |
Enzyme Information
| 6.2.1.- |
Acid--thiol ligases.
based on mapping to UniProt Q8TBC4
|
UniProtKB Entries (1)
| Q13564 |
ULA1_HUMAN
Homo sapiens
NEDD8-activating enzyme E1 regulatory subunit
|
PDB Structure
| PDB | 1R4N |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | Escherichia |
| Primary Citation |
The structure of the APPBP1-UBA3-NEDD8-ATP complex reveals the basis for selective ubiquitin-like protein activation by an E1.
Mol.Cell
|