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1 keywords

CATH Domain 1qwtB00

CATH Classification

Level CATH Code Description
Class 2 Mainly Beta
Architecture 2.60 Sandwich
Topology 2.60.200 Tumour Suppressor Smad4
Homologous Superfamily 2.60.200.10  

Domain Context

CATH Clusters

Superfamily 2.60.200.10
Functional Family Interferon regulatory factor 3

Enzyme Information

UniProtKB Entries (1)

Q14653
IRF3_HUMAN
Homo sapiens
Interferon regulatory factor 3

PDB Structure

PDB 1QWT
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Crystal structure of IRF-3 reveals mechanism of autoinhibition and virus induced phospho-activation
Qin, B.Y., Liu, C., Lam, S.S., Srinath, H., Delston, R., Correia, J.J., Derynck, R., Lin, K.
Nat.Struct.Biol.
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