CATH Classification
Level | CATH Code | Description |
---|---|---|
3 | Alpha Beta | |
3.40 | 3-Layer(aba) Sandwich | |
3.40.50 | Rossmann fold | |
3.40.50.300 | P-loop containing nucleotide triphosphate hydrolases |
Domain Context
CATH Clusters
Superfamily | P-loop containing nucleotide triphosphate hydrolases |
Functional Family | Estrogen sulfotransferase |
Enzyme Information
2.8.2.2 |
Alcohol sulfotransferase.
based on mapping to UniProt O00204
3'-phosphoadenylyl sulfate + an alcohol = adenosine 3',5'-bisphosphate + an alkyl sulfate.
-!- Primary and secondary alcohols, including aliphatic alcohols, ascorbate, chloramphenicol, ephedrine and hydroxysteroids, but not phenolic steroids, can act as acceptors (cf. EC 2.8.2.15).
|
UniProtKB Entries (1)
O00204 |
ST2B1_HUMAN
Homo sapiens
Sulfotransferase family cytosolic 2B member 1
|
PDB Structure
PDB | 1Q1Z |
External Links | |
Method | X-RAY DIFFRACTION |
Organism | Escherichia |
Primary Citation |
Crystal structure of human cholesterol sulfotransferase (SULT2B1b) in the presence of pregnenolone
and 3'-phosphoadenosine 5'-phosphate. Rationale for specificity differences between prototypical
SULT2A1 and the SULT2BG1 isoforms.
J.Biol.Chem.
|